During the Dominion War, many of the Galaxy hulls mothballed at Utopia Planitia Yards at Mars were activated and put back into the construction lines. The dire need for new heavy warships was mounting as casualty reports from the front lines continued to stream in at a dizzying pace.

It was decided that a slight upgrade would be made to the superstructures of the new construction Galaxies to increase their overall firepower. Cargo and other non-combat systems were carved from the hull to make room for heavier weapons. The end result was a slightly more powerful Galaxy design.

The uprated Galaxy Heavy Command Ships moved to the front lines and replaced those command vessels that had fallen during the previous months of the war. After the end of the Dominion War most of these Galaxies were put back in mothballs or converted back to standard models.